Side Effects of Antidiabetic Drug

Side Effects of Antidiabetic Drug

Side effect is an unwanted issue that is caused by a medicine. Diabetes medication unfortunately includes common side effects such as nausea or an upset stomach. Often in the case of diabetes drugs like Metformin, the side effects will only be temporary.

Potential side effects of diabetes drug

1. Sulfonylureas: The primary side effect is hypoglycemia and minor skin allergy and also low blood sugar, skin rash, upset stomach and weight gain.

2. Meglitinides: The primary side effect is hypoglycemia and minor symptoms are skin rash or itching, gastro-intestinal upset, low blood sugar and weight gain

3. Thiazolidinediones: The medication may cause fluid retention, anaemia risk, edema or weight gain, risk of liver disease, swelling of legs and ankles. 

4. Biguanides: The side effect is lactic acidosis, especially using for those who were comorbid with obvious heart failure or liver/renal function impairment. The minor side effects are nausea, diarrhea and gastro-intestinal upset. Also, kidney complications, tiredness or dizziness are observed sometimes.

5. Alpha-glucosidase inhibitors: The serious side effect is liver function impairment and the less annoying side effects are flatulence or diarrhea, gas, bloating.

Diabetes Pills	Side Effects
Biguanides Metformine	Bloating, gas, diarrhea, upset stomach, loss of appetite (usually within the first few weeks of starting). In rare cases, lactic acidosis may occur in people with abnormal kidney or liver function.
Sulfonylureas Glimepiride  Glyburide Glipizide	Low blood glucose, occasional skin rash, irritability, upset stomach.
Meglitinides Repaglinide D-Phenylalanin Derivatives Nateglinide	Effects diminish quickly and they must be taken with each meal; may cause low blood glucose.
Thiazolidinediones Pioglitazone	May cause side effects such as swelling (edema) or Fluid retention.
DPP-4 Inhibitors Sitagliptin Saxagliptin Linagliptin	Stomach discomfort, diarrhea, sore throat, stuffy nose, upper respiratory infection. Do not cause low blood glucose.
Alpha-glucosidase Inhibitors Acarbose Miglitol	Gas, diarrhea, upset stomach, abdominal pain
Bile Acid Sequestrants Colesevelam	Constipation, nausea, diarrhea, gas, heartburn, headache (may interact with glyburide, levothyroxine and contraceptives)